Using Aerofly FS 2, I have a suggestion.
As the number of airports and regions climbs, the current means of choosing an airport by physically moving the cursor across the map is going to become more and more clumsy.
I suggest it would probably be good to make it possible to search by Icao, or by city/state/country or airport name, sooner rather than later, before things get totally out of hand.
EDIT: Maybe as you type, the map could move to show the selected area?