You can create a basic route with the flight plan menu by selecting your origin and destination airport.
Then in the sim you can tell the EC135 to fly the route by selecting the NMS navigation source (should already be set per default I think) and then push the NAV button on the autopilot once you are in the air.
See the wiki page for more infos on how to use the EC135 autopilot: https://www.aerofly.com/dokuwi…aircraft:ec135_helicopter
Thank you very much for your quick response, when you tell me to activate the autopilot, does this mean that I will fly the ec135 for me ???, I am the one who wants to pilot the ec135, not that the machine does it for me, my ignorance in these matters are great. Another question if you are so kind, I want to pilot the ec135 in realistic mode, I read in a message of yours hsce time that for this you have to press a red button on the helicopter to be able to pilot it without any help, where is that red button? ??
Thank you very much for helping this beginner.