I think I may have found where some of the issue was...
In searching around for potential solutions, I came across these links:
TrackIR software uninstall/reinstall process
In doing a registry search, I found that my system had 8 different entries under the HKEY_LOCAL_MACHINE - SYSTEM - CONTROLSETxxx - ENUM - USB - Vid_xxxxxx set of keys associated with my TrackIR device. I am not completely sure how Windows 10 handles USB port assignments in the registry, but that was quite a bit more than any of my other devices. After uninstalling the TrackIR software and disconnecting my device, I carefully cleaned those entries from my registry along with the obsolete registry entries recommended by the TrackIR support people.
Lo and behold, this time after reinstalling the TrackIR software, the performance was butter-smooth - stutters almost 100% gone. Absolutely night-and-day difference, even with the default profiles and smoothness at the default setting.
I think in my case, each time that the TrackIR had been disconnected and moved to a different USB port, the software may have left these duplicate keys in the registry. Either that was the issue, or the TrackIR software simply isn't very good at cleaning up after itself. Either way, following this process seemed to completely fix the problem for me. I have my TrackIR now on a 4-port USB pci-e card with separate controllers for each port, and I am not moving it now that it is working!
I would only caution anyone to make sure you know what you are doing before messing with the registry, as you can really mess things up if you delete the wrong thing.