First check if there is a newer graphics card driver available for your specific hardware. Visit the homepages of your graphics card manufacturer and search for your graphics card and download newer drivers.
If updating the graphics card drivers did not help lowering the graphics settings can help as well, especially if the installed graphics card is at the lower end of the recommended range. From the Aerofly FS 2 main menu click on the “Settings” button and then on the “Graphics” button to open the graphics settings.
Use the arrow buttons for the resolution setting at the top to select the “window mode”. This should bring a significant significant relief to the graphics card. If that doesn't help try lowering the graphics quality setting.