For a very long time I suffered whenever I tried to use Aerofly FS 2 in Vulkan mode. The fps rate is great, but there was always some CTD.
So I tried to use OpenGL. Stability improved, but on the other hand the fps dropped too much and I had stutters. I don't blame the simulator, but my laptop, which has a configuration not ideal for games (A12 mobile + RX540 + 8gb single channel).
So I decided to do a lot of tests. The Vulkan's fluidity is unbeatable and I was willing to be able to fly without the CTDs.
I was able to figure out an ideal situation to test. There was always the CTD. Just take-off from outside the San Francisco region towards that city.
Finally, after testing a lot of things, I came up with the crazy idea of installing a 2018 driver, specifically 18.10.1 without AMD software.
BINGO! No problem flying with ULTRA graphics in any default scenario.
AMD drivers is a crazy thing. They solve some things and spoil others.
Here's a tip: Old drivers